Effect of Intranasal Dexmedetomidine Combined with Epidural Block Anesthesia on Perioperative Hemodynamic Stability in Elderly Patients with Hip Fracture
Objectives To analyze the effect of Intranasal Dexmedetomidine combined with iliac fascia epidural block anesthesia on perioperative hemodynamic stability in elderly patients with hip fracture.Methods A total of 66 elderly patients with perioperative hip fracture admitted to our hospital from February 2020 to February 2023 were randomly divided into control group and observation group,with 33 cases in each group.The control group underwent iliac fascia epidural block anesthesia,while the observation group underwent Intranasal Dexmedetomidine combined with iliac fascia epidural block anesthesia.The anesthetic effects of the two groups were compared.Re-sults During anesthesia,there was no significant difference in hemodynamic indexes between the two groups(P＞0.05).The hemodynamic SBP,DBP,heart rate and blood oxygen saturation of the observation group were signifi-cantly better than those of the control group at the beginning of the operation,at the time of balloon dilatation and bone cement injection,and at the end of operation(P＜0.05).The VAS scores of the observation group were signifi-cantly lower than those of the control group at 12 h,1d and 2 d after operation(P＜0.05).The operation time,exhaust time,hospitalization time and ambulation time of the contro group were significantly shorter than those of the obser-vation group,and the intraoperative blood loss of the contro group was significantly less than that of the observation group(P＜0.05).Conclusions Intranasal Dexmedetomidine combined with iliac fascia epidural block anesthesia for elderly hip fracture surgery has high safety and good sedative effect,and can improve patient comfort.
DexmedetomidineNasal dripIliac fascia epidural block anesthesiaHip fracture in the elderly
万方数据
维普
