Research Progress on the Association Between Short-term Glycemic Variability andTime in Range and Diabetic Retinopathy
Glycated hemoglobin is currently the"gold standard"for evaluating glycemic control and predicting chronic complications of diabetes.However,many studies show that glycosylated hemoglobin has limitations in comprehensively evaluating glycemic control,and patients with well-controlled glycosylated hemoglobin are still at the risk of diabetic retinopathy,suggesting that we need to introduce new evaluation indicators to establish its association with diabetic retinopathy.Existing studies show that short-term glycemic fluctuations are associated with diabetic retinopathy,and indicators such as time in range for continuous glucose monitoring can predict diabetic retinopathy grade.This article aims to review the correlation between blood glucose fluctuation and diabetic retinopathy from both basic and clinical studies,in order to provide a new basis for the prevention and treatment of diabetic retinopathy.