首页|短期血糖变异性和葡萄糖目标范围内时间与糖尿病视网膜病变相关性的研究进展

短期血糖变异性和葡萄糖目标范围内时间与糖尿病视网膜病变相关性的研究进展

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糖化血红蛋白是目前评价血糖控制及预测糖尿病慢性并发症的"金标准",然而许多研究表明糖化血红蛋白在全面评估血糖控制方面有局限性,并且糖化血红蛋白控制良好的患者依然存在糖尿病视网膜病变风险,这提示我们需要引入新的评价指标建立其与糖尿病视网膜病变的关联性.现有研究表明,短期血糖波动与糖尿病视网膜病变相关,动态血糖监测可获得的葡萄糖目标范围内时间等指标可以预测糖尿病视网膜病变分级.本文旨在从基础及临床研究两方面对血糖波动与糖尿病视网膜病变的相关性进行综述,以期为糖尿病视网膜病变防治提供新依据.
Research Progress on the Association Between Short-term Glycemic Variability andTime in Range and Diabetic Retinopathy
Glycated hemoglobin is currently the"gold standard"for evaluating glycemic control and predicting chronic complications of diabetes.However,many studies show that glycosylated hemoglobin has limitations in comprehensively evaluating glycemic control,and patients with well-controlled glycosylated hemoglobin are still at the risk of diabetic retinopathy,suggesting that we need to introduce new evaluation indicators to establish its association with diabetic retinopathy.Existing studies show that short-term glycemic fluctuations are associated with diabetic retinopathy,and indicators such as time in range for continuous glucose monitoring can predict diabetic retinopathy grade.This article aims to review the correlation between blood glucose fluctuation and diabetic retinopathy from both basic and clinical studies,in order to provide a new basis for the prevention and treatment of diabetic retinopathy.

Glucose VariabilityTIRDiabetic Retinopathy

石茗西、王君、梁真

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暨南大学第二临床医学院内分泌科,广东 深圳 518020

血糖波动 葡萄糖目标范围内时间 糖尿病视网膜病变

2024

现代诊断与治疗
南昌市医学会 南昌市医学科学研究所

现代诊断与治疗

影响因子:0.736
ISSN:1001-8174
年,卷(期):2024.35(2)
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