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柴胡疏肝散联合莫沙必利治疗老年功能性消化不良的效果

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目的 探讨柴胡疏肝散联合莫沙必利治疗老年功能性消化不良(Functional dyspepsia,FD)的效果.方法 选取我院 2018 年 6 月至2023 年 6 月收治的 82 例老年FD患者为研究对象,根据治疗方法不同分为对照组和观察组各41 例.对照组给予莫沙必利治疗,观察组给予莫沙必利联合柴胡疏肝散治疗.对比两组中医证候积分、治疗效果、胃排空率和心理状态.结果 治疗后,两组中医证候积分主症、次症及总症状积分均低于治疗前,且观察组低于对照组(P<0.05);观察组治疗总有效率显著高于对照组(P<0.05);治疗后,两组SDS、SAS评分均明显低于治疗前,胃排空率显著高于治疗前,且观察组SDS、SAS评分显著低于对照组,胃排空率显著高于对照组(P<0.05).结论 柴胡疏肝散联合莫沙必利治疗老年FD,疗效显著,可有效改善患者的临床症状,缓解抑郁和焦虑情绪,提高胃排空功能,且安全性良好.
Effect of ChaihuShugan San Combined with Mosapride in the Treatment of Elderly Functional Dyspepsia
Objectives To investigate the effect of ChaihuShugan San combined with Mosapride in the treatment of elderly functional dyspepsia(FD).Methods A total of 82 elderly FD patients admitted to our hospital from June 2018 to June 2023 were selected and divided into control group and observation group according to the treatment methods,with 41 patients in each group.The control group was treated with Mosapride,and the observation group was treated with Mosapride combined with ChaihuShugan San.The TCM syndrome score,treatment effect,gastric emptying rate,and psychological status were compared between the two groups.Results After treatment,the TCM syndrome scores of main symptoms,secondary symptoms and total symptoms of both groups were significantly decreased compared to those before treatment(P<0.05),and those in the observation group were significantly lower than those in the control group(P<0.05).The total effective rate of treatment in the observation group was significantly higher than that in the control group(P<0.05).After treatment,the SDS and SAS scores of the two groups were significantly lower than those before treatment,and the gastric emptying rate was significantly higher than that before treatment(P<0.05).Especially,the decrease/increase amplitude of the observation group was significantly greater than that of the control group(P<0.05).Conclusions ChaihuShugan San combined with Mosapride has a definite therapeutic effect on elderly FD,which can effectively improve the clinical symptoms of patients,relieve depression and anxiety,improve gastric emptying function,and has good safety.

ChaihuShugan SanMosaprideElderl

王婷

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天津市河东区中医医院,天津 300160

柴胡疏肝散 莫沙必利 老年功能性消化不良

2024

现代诊断与治疗
南昌市医学会 南昌市医学科学研究所

现代诊断与治疗

影响因子:0.736
ISSN:1001-8174
年,卷(期):2024.35(14)