Research Progress on Recurrence Mechanism of Childhood Acute Lymphoblastic Leukemia
Childhood Acute Lymphoblastic Leukemia(ALL)is a malignant hematological disease that originates from lymphoid B and T cells and proliferates abnormally in the bone marrow.Chemotherapy is the main method forthe treatmentof the disease,with a high cure rate.However,many children still relapse after treatment,and the specific recurrence mechanism has not beenfully understoodso far.We hope to clarify the mechanism of relapse by conduct-ing large sample data research and large sample disease cohort follow-up,so as to carry out individualized treat-ment and promote the development and progress of clinical diagnosis and treatment technology for childhood ALL.