儿童急性淋巴细胞白血病复发机制研究进展
Research Progress on Recurrence Mechanism of Childhood Acute Lymphoblastic Leukemia
张婷 1姚秀云1
作者信息
摘要
儿童急性淋巴细胞白血病(ALL)是从淋巴B、T细胞起源,并在骨髓内异常增生的一种恶性血液系统疾病.化疗是治疗该病的主要手段,有着较高的治愈率,但治疗后很多患儿的病情依然会复发,且目前对于其具体复发机制还未完全清楚.希望通过开展大样本数据研究及大样本疾病队列随访来明确其复发机制,据此进行个体化治疗,进而推动儿童ALL临床诊治技术的发展及进步.
Abstract
Childhood Acute Lymphoblastic Leukemia(ALL)is a malignant hematological disease that originates from lymphoid B and T cells and proliferates abnormally in the bone marrow.Chemotherapy is the main method forthe treatmentof the disease,with a high cure rate.However,many children still relapse after treatment,and the specific recurrence mechanism has not beenfully understoodso far.We hope to clarify the mechanism of relapse by conduct-ing large sample data research and large sample disease cohort follow-up,so as to carry out individualized treat-ment and promote the development and progress of clinical diagnosis and treatment technology for childhood ALL.
关键词
儿童/急性淋巴细胞白血病/复发机制/研究进展Key words
Children/Acute lymphoblastic leukemia/Recurrence mechanism/Research progress引用本文复制引用
出版年
2024
NETL
NSTL
万方数据