Study on the Intervention of QingweiBupi Decoction Combined with Lipoic Acid Injection on Early Type 2 Diabetes Mellitus
Objectives To explore the intervention effect of QingweiBupi Decoction combined with lipoic acid injection on early type 2 diabetes mellitus(T2DM).Methods A total of 120 patients with early T2DM admitted to our hospital from October 2021 to September 2023 were selected as the research objects.The patients were randomly divided into lipoic acid group,traditional Chinese medicine group,lipoic acid combined with traditional Chinese medicine group,and control group by random number table method,with 30 cases in each group.The blood glucose,urinary microalbumin(ALB),fasting and 2h postprandial insulin levels of the 4 groups were compared.Results After 2 weeks of treatment,the fasting blood glucose(FBG),2h postprandial blood glucose(2hPG),glycated hemoglobin(HbAlc)and urinary ALB of lipoic acid combined with Chinese medicine group were significantly lower than those of lipoic acid group,Chinese medicine group and control group,and those of lipoic acid group and Chinese medicine group were significantly lower than those of control group(P<0.05).After 2 weeks of treatment,fasting and 2h postprandial insulin levels of the four groups were increased,and those in the lipoic acid combined withChinese medicine group were significantly higher than those of the lipoic acid group,Chinese medicine group and control group,and those in the lipoic acid group and Chinese medicine group were significantly higher than that of the control group(P<0.05).Conclusions QingweiBupi Decoction combined with lipoic acid injection can improve the level of blood glucose and insulin in early T2DM patients and reduce the level of urinary ALB.
Type 2 diabetes mellitusQingweiBupi DecoctionLipoic acid injectionBlood glucoseInsulin
万方数据
维普
