Effect of Golden Clam oral liquid on immunologic function of mice with acute radiation sickness
Objective It is to approach the influence of Golden Clam oral liquid (GCOL) on immunologic function of blood-weak mouse model exposed with X ray. Methods 60 mice were divided into 5 groups, 12 cases in each group. All animals were treated by intragastric administration with high, middle and low dose GCOL or physiological saline for 6 days. The mice immune dysfunction model excepted control group were established by exposed with X ray. The changes of weight-carrying swimming time, step-down wrong times and immune organs (thymus, spleen) weight in each group were detected and compared. Results GCOL could markedly improve the blood-weak weight-carrying swimming time, step-down wrong times and mouse thymus index, but also improve the reticuloendothelial system phagocytic function. Conclusion GDOL enhance the immunologic function on blood-weak mouse model exposed with X ray.