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针刺治疗子宫腺肌病痛经疗效观察

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目的 观察针刺治疗子宫腺肌病痛经的临床疗效.方法 将 2020 年 12 月—2022年1 月就诊于北京中医药大学东直门医院及通过海报招募的71 例子宫腺肌病痛经患者随机分为试验组38 例和对照组33 例.试验组采用针刺治疗,经期每天针刺1 次,非经期每周针刺2 次,每次均留针30 min;对照组于经期口服布洛芬缓释胶囊,1 粒/次,2 次/d,连服5d;2 组均治疗3 个月经周期.观察2 组治疗前后经期最痛视觉模拟(VAS)评分、月经失血图(PBAC)评分、COX痛经症状量表(CMSS)评分、生活质量量表(EHP-5)评分及不良反应发生情况.结果 治疗第1,2,3 个月经周期,2 组VAS评分及试验组PBAC评分均较治疗前明显降低(P均<0.05);随治疗周期延长,试验组VAS 评分、PBAC 评分均逐渐降低,各时间点两两比较差异均有统计学意义(P 均<0.05),对照组各时间点VAS评分、PBAC评分两两比较差异均无统计学意义(P均>0.05).治疗第1 个月经周期,对照组VAS评分明显低于试验组(P<0.05);2 组治疗第2 和第3 个月经周期的VAS评分和治疗第1,2,3 个月经周期的PBAC评分比较差异均无统计学意义(P均>0.05).治疗第3 个月经周期,2 组CMSS严重程度和持续时间评分、EHP-5 评分均较治疗前明显降低(P均<0.05);2 组治疗第3 个月经周期CMSS严重程度和持续时间评分、EHP-5 评分、治疗第 3 个月经周期与治疗前的CMSS严重程度和持续时间评分差值、治疗第3 个月经周期与治疗前的VAS评分差值比较差异均无统计学意义(P均>0.05),试验组治疗第3 个月经周期与治疗前的PBAC评分差值和EHP-5 评分差值均明显高于对照组(P均>0.05).2 组不良反应均轻微.结论 针刺与布洛芬胶囊在减轻子宫腺肌病患者痛经严重程度和改善痛经伴随症状方面疗效相当,但针刺在减少月经量和提高生活质量方面可能更有优势.
Therapeutic effect of acupuncture on secondary dysmenorrhea caused by adenomyosis
Objective It is to observe the clinical efficacy of acupuncture in the treatment of dysmenorrhea in adenomy-osis.Methods Seventy-one dysmenorrheal patients with adenomyosis who visited Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine and were recruited through posters from December 2020 to January 2022 were randomly di-vided into 38 cases in the test group and 33 cases in the control group.The experimental group was treated with acupunc-ture,once daily during menstruation and twice per week during non menstruation,the needle remaining time was 30 mi-nutes;the control group was given ibuprofen sustained-release capsules orally during menstruation,one capsule per time,twice daily day,continuously treated for 5 days.Both groups were treated for 3 menstrual cycles.The scores of menstrual worst pain visual analog scale(VAS),pictorial blood loss assessment chart(PBAC),menstrual blood loss chart(PBAC),COX menstrual symptom scale(CMSS),endometriosis health profile-5(EHP-5)before and after treatment,and the incidence of adverse reactions were observed in the two groups.Result The VAS scores of the two groups and the PBAC scores of the experimental group in the 1st,2nd and 3rd menstrual cycles of treatment were significantly lower than those before treatment(all P<0.05);with the prolongation of the treatment cycle,the VAS scores and PBAC scores of the experimental group were gradually reduced,and the differences at each time point were statistically significant after pairwise comparisons(all P<0.05),but the differences at each time point were not statistically significant in the control group(all P>0.05).In the 1st menstrual cycle of treatment,the VAS score of the control group was significantly lower than that of the experimental group(P<0.05);the differences in the VAS scores of the 2nd and3rd menstrual cycles of treatment and the PBAC scores of the 1st,2nd,and 3rd menstrual cycles of treatment were not statistically significant between the two groups(all P>0.05).In the 3rd menstrual cycle of treatment,the CMSS severity and duration scores and EHP-5 scores of the two groups were significantly lower than those before treatment(all P<0.05);the differences in the CMSS severity and duration scores,EHP-5 scores in the 3rd menstrual cycle,and the difference of CMSS severity and duration scores between the 3rd menstrual cycle of treatment and pre-treatment,difference of VAS scores between the 3rd menstrual cycle of treat-ment and pre-treatment were not statistically significant between the two groups(all P>0.05),the difference of PBAC scores and EHP-5 scores between the 3rd menstrual cycle of treatment and pre-treatment in the experimental group were sig-nificantly higher than those in the control group(all P<0.05).Adverse effects in the two groups were mild.Conclusion Acupuncture and ibuprofen capsule are equally effective in reducing the severity of pain and improving the symptoms associ-ated with dysmenorrhea in patients with adenomyosis,but acupuncture may have more advantages in reducing menstruation and improving quality of life.

adenomyosisdysmenorrheaacupunctureibuprofen

王美红、李晓屏、赵吉平

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湖南中医药大学第一附属医院 ,湖南 长沙 410007

北京中医药大学东直门医院,北京 100700

子宫腺肌病 痛经 针刺疗法 布洛芬胶囊

国家中医药管理局国家中医临床研究基地业务建设科研专项课题

JDZX2015063

2024

现代中西医结合杂志
中国中西医结合学会河北分会,中华中医药学会

现代中西医结合杂志

CSTPCD
影响因子:1.775
ISSN:1008-8849
年,卷(期):2024.33(2)
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