Efficacy of traditional Chinese medicine based on differentiation on hypertension with insomnia
Objective It is to evaluate the effectiveness and safety of traditional Chinese medicine based on differentia-tion in the treatment of hypertension with insomnia.Methods The patients with hypertension with insomnia treated in the Affiliated Hospital of Henan Academy of Traditional Chinese Medicine and Henan Provincial People's Hospital from January 2019 to June 2021 were selected as the study subjects,and a prospective non-randomized controlled study method was used to classify the patients into the group of integrated traditional Chinese and western medicine(combination group)and west-ern medicine group according to whether they were treated with traditional Chinese medicine or not,and 137 pairs of pa-tients were matched with 137 cases in each group by the propensity score method.Both groups were treated with amlodipine benzenesulfonate combined with eszopiclone,and the combination group was additionally treated with traditional Chinese medicine based on differentiation,both groups were treated for 8 weeks.The blood pressure,scores of Pittsburgh Sleep Quality Index(PSQI)and traditional Chinese medicine syndromes of patients before and after treatment were compared be-tween the two groups,and the efficacies of blood pressure,insomnia,and traditional Chinese medicine syndromes in the two groups were assessed.Results After 8 weeks of treatment,the blood pressure,PSQI score and traditional Chinese med-icine syndrome scores of the two groups were significantly lower than those before treatment(all P<0.05),and the blood pressure,PSQI score and traditional Chinese medicine syndromes of the combination group were significantly lower than those of the control group(all P<0.05).After8 weeks of treatment,the total effective rates of blood pressure,insomnia,and traditional Chinese medicine syndromes in the combination group were93.38%(127/136,with1 case dropped in this group),81.02%(111/137),and 94.89%(130/137),respectively,which were significantly higher than those(81.02%(111/137),43.80%(60/137),68.61%(94/137)of the western medicine group,and the differences were all statistically significant(all P<0.05).Conclusion Therapy with traditional Chinese medicine based on differentiation can effectively reduce the blood pressure of patients with hypertension with insomnia,improve their sleep quality and allevi-ate clinical symptoms.
hypertensioninsomniadifferentiation and treatment of Chinese medicine
万方数据
维普
