Efficacy of decoction for clearing heat,resolving phlegm,tranquilizing spirit on insomnia of type of lung un-storing soul with syndrome of phlegm-heat accumulating lung
Objective It is to investigate the clinical efficacy of decoction for clearing heat,resolving phlegm,tranquil-izing spirit on insomnia of type of lung un-storing soul with syndrome of phlegm-heat accumulating lung.Methods A total of 96 patients with insomnia of type of lung un-storing soul with syndrome of phlegm-heat accumulating lung who were collect-ed from Sleep Expert Outpatient Clinic of the Inheritance Workshop of National Famous Elderly Chinese Medicine Experts and Psychiatry Outpatient Clinic of the Fourth Affiliated Hospital of Xinjiang Medical University from January 1 to Decem-ber 31,2023 were divided into traditional Chinese medicine(TCM)group and western medicine group according to ran-domised controlled method,with 48 cases in each group.The western medicine group was treated with zolpidem tartrate tablets,and the TCM group was treated with decoction for clearing heat,resolving phlegm,tranquilizing spirit,both groups were treated for 28 days.The scores of 6 dimensions and total scores of Pittsburgh Sleep Quality Index(PSQI),the scores of each individual item and total scores of TCM syndromes before and after treatment,the total score reduction rate of PSQI and TCM syndrome after the treatment of patients in the two groups were compared,and the occurrence of adverse reactions during the treatment period,the recurrence situation after discontinuation of medication,and the time from discontinuation of medication to the recurrence of the disease of patients in the two groups were recorded.Results After treatment,the total scores of PSQI and TCM syndrome of both groups were significantly lower than those before treatment(all P<0.05),and the total scores of the TCM group were lower than those of the western medicine group(all P<0.05);the scores of 6 di-mensions of PSQI of the two groups,the scores of each individual item of TCM syndromes of the TCM group,and the scores of light sleepiness and irritability of the western medicine group were significantly lower than those before treatment(all P<0.05),the scores of sleep quality and sleep disorder of PSQI,the scores of TCM symptoms such as light sleepiness,chest tightness and palpitation,dizziness or headache,phlegm and sticky mouth,bitter mouth and bad breath,and dry stools of the TC group compared were significantly lower than those of the western medicine group(all P<0.05).The reduction rates of PSQI and TCM syndromes of the TCM group were significantly higher than those of the western medicine group after treatment(both P<0.05).Headache,dizziness and drowsiness occurred in both groups during treatment,and the inci-dence of total adverse reactions was significantly lower in the TCM group than that in the western medicine group[9.3%(4/43)VS.35.7%(15/42),P<0.05].After discontinuation of medication,the recurrence rate was significantly lower in the TCM group than that in the western medicine group[16.3%(7/43)VS.40.5%(17/42),P<0.05],and the time from discontinuation of medication to the recurrence of the disease was significantly longer than that in the western medicine group(P<0.05).Conclusion Decoction for clearing heat,resolving phlegm,tranquilizing spirit can effectively improve the sleep quality and alleviate the uncomfortable symptoms of patients with insomnia of type of lung un-storing soul with syndrome of phlegm-heat accumulating lung,and reduce the recurrence rate and occurrence rate of adverse reactions.
insomnia of type of lung un-storing soulsyndrome of phlegm-heat accumulating lungdecoction for clear-ing heat,resolving phlegm,tranquilizing spiritsleep quality
万方数据
维普
