Distribution and cluster analysis of traditional Chinese medical syndrome elements in premature ovarian failure
Objective It is to investigate the distribution of traditional Chinese medicine(TCM)syndromes and syn-dromes elements and their correlation in women with premature ovarian failure(POF).Methods The case data of patients with POF treated in the obstetrics and gynecology clinic of Shenzhen Hospital of Guangzhou University of Chinese Medicine(Futian)from January 1,2019 to October 31,2023 were collected,and the TCM syndrome types and syndrome elements were standardized.The association analysis and cluster analysis were performed by SPSS Statistics 27.0 and SPSS Modeler 18.0 soft in the syndrome elements to explore the potential relationships among the evidence elements of POF.Results A total of 104 outpatient cases were collected,and after standardization,a total of 14 common TCM syndrome types were ob-tained,in which the highest frequency of syndomre type was spleen and kidney Yang deficiency.A total of 10 syndrome el-ements were extracted,the main disease site was kidney,and the main disease nature was Qi deficiency,Yin deficiency and Yang deficiency.Association analysis showed that the combination with the highest support and confidence was kidney-Yin deficiency.Conclusion Spleen-kidney Yang deficiency syndrome and Kidney essence deficiency syndrome are common syndromes of POF,kidney-Yin deficiency is the strongest combination of syndrome elements associated with POF.
premature ovarian failuretraditional Chinese medicine syndrome typesyndrome elementcorrelation a-nalysiscluster analysis