首页|浮针联合补肾活血汤治疗肾虚血瘀型骨质疏松性椎体压缩骨折椎体成形术后残余疼痛的研究

浮针联合补肾活血汤治疗肾虚血瘀型骨质疏松性椎体压缩骨折椎体成形术后残余疼痛的研究

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目的 探讨浮针联合补肾活血汤治疗肾虚血瘀型骨质疏松性椎体压缩骨折(OVCF)椎体成形术后残余疼痛的疗效及机制.方法 采用随机数字表法,将2022 年8 月—2023 年6 月在贵阳市第四人民医院治疗的60 例肾虚血瘀型OVCF椎体成行术后残余疼痛患者分为浮针联合补肾活血汤组、普通刺法联合补肾活血汤组和对症止痛组,每组 20 例.3 组常规抗骨质疏松治疗 6个月,浮针联合补肾活血汤组予浮针治疗2 周和口服补肾活血汤6 个月,普通刺法联合补肾活血汤组予普通针刺2 周和口服补肾活血汤6 个月,对症止痛组予对症止痛治疗.比较3 组治疗前1d及治疗1 周、2 周、1 个月、3 个月、6 个月后的疼痛VAS评分、Oswestry功能障碍指数(ODI)评分、压痛点数目,治疗前1d及治疗1 周、2 周后的炎症指标[肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)]和治疗前1d及治疗3 个月、6 个月后的骨密度,统计3 组治疗6 个月后的总体疗效.结果 与治疗前1d比较,3 组治疗后各时间点VAS评分、ODI评分、压痛点数目及血清TNF-α、IL-6水平均明显降低(P均<0.05),3 组治疗6 个月后的骨密度度均明显提高(P均<0.05);与普通刺法联合补肾活血汤组及对症止痛组比较,浮针联合补肾活血汤组治疗后各时间点的VAS评分、ODI评分、压痛点数目及血清TNF-α、IL-6 水平均更低(P均<0.05),治疗6 个月后的骨密度更高(P均<0.05).浮针联合补肾活血汤组治疗总有效率为95%(19/20),高于普通刺法联合补肾活血汤组的85%(17/20)及对症止痛组的65%(13/20),差异均有统计学意义(P均<0.05).结论 浮针联合补肾活血汤口服能够有效减轻肾虚血瘀型OVCF椎体成形术后残余疼痛症状,减轻炎症反应,提高骨密度,改善腰椎功能活动.
Floating needle combined with decoction for tonifying kidney and activating blood on residual pain after vertebroplasty for osteoporotic vertebral compression fracture with syndrome of kidney deficiency and blood stasis
Objective It is to explore the efficacy and mechanism of floating needle combined with decoction for tonify-ing kidney and activating blood(DTKAB)on residual pain after vertebroplasty for osteoporotic vertebral compression frac-ture(OVCF)with syndrome of kidney deficiency and blood stasis.Methods Sixty patients with residual pain after verte-broplasty for OVCF with syndrome of kidney deficiency and blood stasis treated in Guiyang Fourth People's Hospital from August 2022 to June 2023 were divided into the group of floating needle+DTKAB,group of normal acupuncture+DTKAB and group of symptomatic analgesia according to a randomized numerical table method,with 20 cases in each group.The three groups were treated with conventional anti-osteoporosis therapy for 6 months,the group of floating needle+DTKAB was treated with floating needle for 2 weeks and with DTKAB by oral administration for 6 months,the group of normal acu-puncture+DTKAB was treated with normal acupuncture for 2 weeks and with DTKAB by oral administration for 6 months,the group of symptomatic analgesia was treated with symptomatic analgesic medicine.The pain VAS scores,Oswestry dys-function index(ODI)scores,number of pressure points one day before treatment and after one week,2 weeks,one month,3 months and 6 months of treatment,and inflammation indexes[tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)]one day before treatment and after one week,2 weeks of treatment,and bone mineral density one day before treatment and after 3 and 6 months of treatment were compared among the three groups,and the overall efficacy of the three groups after 6 months of treatment was assessed.Results Compared with those one day before treatment,the VAS scores,ODI scores,number of pressure points and serum levels of TNF-α and IL-6 were significantly reduced at all time points after treatment in the three groups(all P<0.05),while the bone densities after 6 months of treatment were significantly increased in the three groups(all P<0.05).Compared with the group of normal acupuncture+DTKAB and group of symptomatic analgesi-a,the VAS scores,ODI scores,number of pressure pain points and serum levels of TNF-α and IL-6 at all time points after treatment were significantly lower,while the bone mineral density after 6 months of treatment were significantly higher in the group of floating needle+DTKAB(all P<0.05).The total effective rate of group of floating needle+DTKAB was95%(19/20),which was higher than that 85%(17/20)of group of normal acupuncture+DTKAB and that 65%(13/20)of group of symptomatic analgesia,and the differences were statistically significant(both P<0.05).Conclusion Floating needle combined with oral administration of decoction for tonifying kidney and activating blood can effectively alleviate the residual pain,reduce the inflammatory reaction,increase bone density,and improve the functional activity of lumbar spine after vertebroplasty for osteoporotic vertebral compression fracture with syndrome of kidney deficiency and blood stasis,.

osteoporotic vertebral compression fracturepostoperative residual painfloating needledecoction for tonifying kidney and activating blood

王淑江、叶豪、秦黎勇、龙胜利

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贵州中医药大学,贵州 贵阳 550002

黔西南州中医院,贵州兴义 562400

贵阳市第四人民医院,贵州 贵阳 550007

骨质疏松性椎体压缩骨折 术后残余疼痛 浮针 补肾活血汤

2024

现代中西医结合杂志
中国中西医结合学会河北分会,中华中医药学会

现代中西医结合杂志

CSTPCD
影响因子:1.775
ISSN:1008-8849
年,卷(期):2024.33(20)