In order to study the feasibility of adopting different smoke exhaust modes in two adjacent smoke control zones of flat large space buildings,based on FDS,the effects of fire location,smoke exhaust modes,smoke exhaust and air supplement on smoke temperature distribution,heat layer height and airflow mass flow are compared and analyzed,and the feasibility of adopt-ing different smoke exhaust modes in adjacent smoke control zones of flat large space buildings is discussed.The results show that the single natural smoke exhaust mode has the best smoke ex-haust effect;The smoke exhaust effect of the compound smoke exhaust mode with the effective smoke exhaust area of the exter-nal window of 3.16%of the floor area is better than that of the single mechanical smoke exhaust mode;The mechanical smoke exhaust mode disturbs the smoke stratification,the airflow ex-change between smoke control zones is more intense,and the temperature is higher on the height of personnel characteristics,which is not conducive to the safe evacuation of personnel;The smoke retaining vertical wall can effectively store smoke and de-lay the spread of smoke,and limit the high-temperature smoke in the fire zone.