Objective:To explore the safety and efficiency of bivalirudin in rotational atherectomy for calcified coronary lesions.Methods:From January 2019 to December 2021,182 patients(88 cases in bivalirudin group vs.94 cases in unfractionated heparin group)with severe coronary calcification lesions who underwent rotational atherectomy were enrolled in our study.Clinical data,angiographic characteristics and rotational atherectomy details were analyzed.Complications and major adverse cardiovascular events(MACE)were also documented.Results:Except for one patient in unfractionated heparin group who failed,all other patients successfully underwent Rotational atherectomy and stents were implanted.The perioperative myocardial injury(8.0％vs.18.1％,P=0.044)and total bleeding events(4.5％vs.14.9％,P=0.025)in bivalirudin group was significantly less than that in unfractionated heparin group.No MACE occurred during hospitalization.Conclusions:The use of bivalirudin in rotational atherectomy for calcified coronary lesions could significantly reduce perioperative myocardial injury and the incidence of bleeding events.
维普
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