Objective:To observe the expression of pan-immune inflammation value(PIIV)in patients with ST segment elevation myocardial infarction(STEMI)and its relationship with prognosis.Methods:A total of 272 patients with STEMI were selected and the patients were divided into the low PIIV group(<382.1)and the high PIIV group(≥ 382.1)according to the median PIIV(382.1).The correlation between the expression level of PIIV and major adverse cardiovascular events(MACE)in patients with STEMI were analyzed.Results:Compared with patients in the low PIIV group,patients in the high PIIV group had a higher age and heart rate,lower blood pressure,a higher proportion of patients with hypertension history and type 2 diabetes history,and a higher proportion of MACE events(P<0.05).Compared with patients in the low PIIV group,patients in the high PIIV group had higher white blood cell count,neutrophil count,monocyte count,platelet count,hs CRP,blood glucose,LVEF,and creatinine levels,while lower lymphocyte count(P<0.05).Kaplan Meier analysis showed that the incidence of MACE events in patients with high PIIV was significantly higher than that in patients with low PIIV(P<0.05).The ROC curve results indicate that PIIV has the value of predicting MACE after PCI in STEMI patients,with an AUC of 0.881(95%CI:0.832-0.952,P<0.05).Conclusions:PIIV is an independent predictor of MACE in STEMI patients after PCI and has good predictive value.