Objective:Analysis of clinical and pathological features of intracardiac blood cysts to improve the understanding of rare cardiac tumors.Methods:Six cases of intracardiac blood cysts diagnosed between March 2015 and May 2023 were collected for clinical data analysis and observation of pathomorphologic features,and combined with literature review.Results:A total of two females and four males were included,with an age range of 25 to 59 years and a median age of 52.5 years.The blood cysts were located in the mitral valve in 3 cases,the aortic valve in 1 case,the tricuspid valve in 1 case,and the right atrium in 1 case.Histopathologically,the wall of the capsule is composed of fibrous connective tissue lined with vascular endothelial cells,and hemorrhage and thrombosis are seen in the lumen.Immunohistochemical staining showed CD31(+),CD34(+),D2-40(-),Calretinin(-).All cases were completely resected,and six were followed up after surgery,all of which were alive and recurrence-free.Conclusions:Intracardiac blood cysts are extremely rare benign cardiac tumors,and preoperative examination by echocardiography is highly suggestive of the possibility of this mass,with histopathological examination required for definitive diagnosis.The prognosis for this disease is usually good after complete surgical resection.
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