Objective:To investigate the clinical characteristics as well as risk factors of patients with premature coronary heart disease in different age groups.Methods:A total of 380 patients diagnosed with premature coronary artery disease in outpatient clinics of our hospital from June 2021 to August 2022 were selected as the study subjects,40＜patients'age ≤ 59 for the middle-aged and young group,a total of 150 cases in the middle-aged and young group,59＜patients'age ≤ 65 for the elderly group,a total of 230 cases in the elderly group.The clinical data,laboratory test indexes,influencing factors of coronary heart disease,coronary artery lesions and safety after interventional therapy of the two groups were analyzed by one-way analysis.Factors with statistically significant differences in single-factor analysis were brought into multiple linear regression to analyze the relevant influencing factors.Results:Comparing the general information of patients in the elderly group and the young and middle-aged group,only gender was statistically significant(P＜0.05).Compared with patients in the young and middle-aged group,patients in the elderly group had significantly higher levels of creatinine(Cr),plasma prothrombin time(PT),and fibrinogen(FIB),but glutamyl transpeptidase(GGT),TG,Hcy,and platelet counts(PLT)were significantly lower than those of the young and middle-aged group in the elderly group,with a statistically significant difference(P＜0.05)The differences were statistically significant(P＜0.05).As a result of multifactorial Logistic regression analysis,Hcy and FIB entered the regression model;compared with patients in the young and middle-aged group,the elderly group had a higher incidence of all three lesions(P＜0.05).Compared with patients in the young and middle-aged group,the elderly group had a greater incidence of total adverse events after coronary angiography(P＜0.05).Conclusions:Differences in clinical laboratory parameters and clinical prognosis of patients with early-onset coronary artery disease in different age groups suggest that there should be some differences in therapeutic regimens in the clinical treatment of coronary artery disease.
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