Objective:To analyze the distribution of ABO,Rh,MN blood groups and antibodies in children with congenital heart disease in order to more precisely and safely supply blood for the clinic.Methods:We collected medical records and blood samples of children who underwent operations for congenital heart disease at our hospital between January 2023 and November 2023.The blood samples were tested for ABO blood type,Rh(C,c,D,E,and e antigen)blood type,MN blood type,and antibody screening.Antibody specificity was identified for children with positive antibody screening.Results:The distribution frequency of ABO blood group types was O type(32.1％)＞B type(29.2％)＞Atype(24.9％)＞AB type(13.8％).Among the ABO blood groups,531 children with O type accounted for the highest proportion.The distribution frequency of Rh blood group antigens was D(99.4％)＞e(93.9％)＞C(88.5％)＞c(62.9％)＞E(50.5％).In children who tested positive for Rh D,the distribution frequency of Rh was Ccee(25.5％)＞CcEe(22.9％)＞C cEe(18.3％)＞CCEe(16.8％)＞CCee(5.5％)＞ccEe(5.1％)＞CCEe(2.0％)＞ccEE(0.7％).The redominant RhD-negative phenotype among children was ccee(30％).Within the MN blood group,the positive rate for the M antigen was 78.4％,while the N antigen exhibited a positive rate of 71.8％,the composition of MN blood group was MN(50.2％)＞MM(28.2％)＞NN(21.6％).The positive rate of irregular antibody screening was 1.3％,and anti-M was the most common in 64.3％.Conclusions:In children with congenital heart disease,the predominant blood groups include O type,Rh-positive Ccee phenotype,and MN blood type.The most prevalent irregular antibody is anti-M.
维普
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