Objective:To explore the occurrence and risk factors associated with postoperative delirium in patients undergoing cardiac surgery.Methods:A retrospective analysis was conducted on 172 patients who underwent open-heart surgery and were admitted to the cardiac surgery ward at Anzhen Hospital in Beijing between March 2020 and September 2020.The group consisted of 105 males and 67 females,with ages ranging from 20 to 82 years old and an average age of(58.5±11.6)years old.Following consultation with a psychiatrist and assessment of delirium using the CAM scale,the patients were divided into a delirium group(83 cases)and a control group(89 cases)for analysis of the clinical characteristics of postoperative delirium and related risk factors.Results:In this study,48.3%(83/172)of patients undergoing cardiac surgery experienced postoperative delirium.The clinical manifestations of delirium were disorientation disorder,sleep-wake cycle disorder,and attention disorder in that order.Logistic multifactorial regression analysis identified advanced age,previous history of cerebrovascular disease,ICU stay,and postoperative hypotension as risk factors for postoperative delirium.Conclusions:Postoperative delirium following cardiac surgery is prevalent and associated with negative symptoms.Risk factors for delirium after cardiac surgery include advanced age,a history of cerebrovascular disease,prolonged ICU stay,and postoperative hypotension.