The relationship between blood pressure variability within a single visit and sleep duration:Based on NHANES database:2015-2018
尹乐然 1房芳 1蒋宏峰1
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作者信息
1. 100029 首都医科大学附属北京安贞医院-北京市心肺血管疾病研究所 实验中心
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摘要
目的:探索睡眠时长与单次访视内血压变异性间的关系.方法:使用2015年至2018年美国国家健康和营养调查(national health and nutrition examination survey,NHANES)数据库的数据集.排除标准为年龄＜20岁、相关睡眠和血压数据缺失及妊娠期妇女.最终纳入了 10 006名参与者,并按照睡眠时间长短,将参与者分为短(＜7h)、中(7～8小时)、长(＞8h)三个睡眠时间组.采用Logistic回归模型,分析不同睡眠时长与血压变异水平的关系.结果:在进行变量调整后结果显示,收缩期变异系数(coefficient of variation,CV)(OR=1.21,95％CI:1.97～1.50,P=0.09)、收缩期标准差(standard deviation,SD)(OR=1.24,95％CI:1.00～1.53,P=0.05)、脉压差(pulsepressure,PP)(OR=1.36,95％CI:1.19～1.92,P=0.001)与短睡眠时间相关.舒张期 CV(OR=1.14,95％CI:0.98～1.33,P=0.09)、舒张期白大衣效应(white coat effect,WCE)(OR=1.24,95％CI:1.02～1.50,P=0.03)、PP(OR=1.36,95％CI:1.15～1.62,P=0.001)、平均动脉压(mean arterial pressure,MAP)(OR=1.37,95％CI:1.15～1.62,P=0.001)、收缩期 WCE(OR=1.23,95％CI:0.96～1.57,P=0.09)、收缩期最大绝对差(maximum absolute difference,MAD)(OR=1.26,95％CI:0.95～1.66,P=0.097)、收缩期 AR23(OR=1.25,,95％CI:0.96～1.62,P=0.093)与长睡眠时间相关.结论:异常睡眠时长与血压变异高相关,这将为血压监测和管理提供新思路.
Abstract
Objective:This study aimed to investigate the relationship between sleep duration and blood pressure variability during a single visit.Methods:The dataset used in this study was obtained from the NHANES database from 2015 to 2018.Participants were excluded if they were younger than 20 years old,lacked relevant sleep and blood pressure data,or were pregnant.A total of 10,006 participants were included in the final analysis.Participants were divided into three sleep duration groups:Short(＜7 hours),medium(7-8 hours),and long(＞8 hours).Logistic regression models were applied to analyze the relationship between different sleep duration and various blood pressure variability parameters.Results:After adjusting for confounding variables,the results showed that short sleep duration was associated with increased odds of systolic CV(OR=1.21,95％CI:1.97-1.50,P=0.09),systolic SD(OR=1.24,95％CI:1.00-1.53,P=0.05),and pulse pressure(OR=1.36,95％CI:1.19-1.92,P=0.001).Additionally,long sleep duration was associated with diastolic CV(OR=1.14,95％CI:0.98-l.33,P=0.09),diastolic WCE(OR=1.24,95％CI:1.02-1.50,P=0.03),pulse pressure(OR=1.36,95％CI:1.15-1.62,P=0.001),mean arterial pressure(OR=1.37,95％CI:1.15-1.62,P=0.001),systolic WCE(OR=1.23,95％CI:0.96-1.57,P=0.09),systolic MAD(OR=1.26,95％CI:0.95-1.66,P=0.097),and systolic AR23(OR=1.25,95％CI:0.96-1.62,P=0.093).Conclusions:Abnormal sleep duration is correlated with high blood pressure variation,which will provide new ideas for blood pressure monitoring and management.
关键词
美国国家健康和营养调查数据库/睡眠时长/血压变异性
Key words
National health and nutrition examination survey/Sleep duration/Blood pressure variability
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