Effect of radiofrequency ablation of great saphenous vein trunk combined with sclerosing agent injection and punctate exfoliation in the treatment of primary great saphenous varicose veins
Effect of radiofrequency ablation of great saphenous vein trunk combined with sclerosing agent injection and punctate exfoliation in the treatment of primary great saphenous varicose veins
Objective:To explore the effect of radiofrequency ablation of great saphenous vein trunk combined with sclerosing agent injection and punctate exfoliation in the treatment of primary great saphenous varicose veins.Methods:A total of 102 patients with primary great saphenous varicose veins admitted to department of vascular surgery of our hospital were randomly collected as the research subjects.According to the simple randomization method,the patients were divided into control group(n=51)and trial group(n=51).The control group was treated with radiofrequency ablation of great saphenous vein trunk,and the trial group was given radiofrequency ablation of great saphenous vein trunk combined with sclerosing agent injection and punctate exfoliation.The surgical time,numerical rating scale(NRS)at 24 hours after surgery,hospital stay,incidence of postoperative complications,venous clinical severity score(VCSS)and chronic venous insufficiency questionnaire-14(CIVIQ-14)before surgery and at 1 month after surgery,coagulation function[fibrinogen(Fib),plasminogen activator inhibitor-1(PAI-1)]before surgery and at 7 days after surgery and recurrence at 6 months after surgery were compared between two groups of patients.Results:There was no difference in the surgical time between the two groups(P＞0.05).The NRS score at 24 hours after surgery and hospital stay in trial group were lower or shorter than those in control group(P＜0.05).The incidence rate of complications within 7 days after surgery was lower in trial group than that in control group(P＜0.05).At 1 month after surgery,the VCSS score in trial group was lower than that in control group while the CIVIQ-14 score was higher than that in control group(P＜0.05).The levels of Fib and PAI-1 in trial group at 7 days after surgery were lower compared with those in control group(P＜0.05).The recurrence rate in trial group was lower compared to control group(P＞0.05).Conclusions:Radiofrequency ablation of great saphenous vein trunk combined with sclerosing agent injection and punctate exfoliation in the treatment of primary great saphenous varicose veins can shorten the surgical time,reduce the pain degree at 24 hours after surgery,shorten the hospital stay,relieve the venous clinical severity and chronic venous insufficiency,improve the coagulation function,and reduce the recurrence rate.
维普
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