心肺血管病杂志2024,Vol.43Issue(11) :1155-1159,1167.DOI:10.3969/j.issn.1007-5062.2024.11.05

大肠埃希菌所致感染性心内膜炎临床分析

Clinical analysis of infective endocarditis caused by Escherichia coli

黄艳 叶晓芳 朱光发
心肺血管病杂志2024,Vol.43Issue(11) :1155-1159,1167.DOI:10.3969/j.issn.1007-5062.2024.11.05

大肠埃希菌所致感染性心内膜炎临床分析

Clinical analysis of infective endocarditis caused by Escherichia coli

黄艳 1叶晓芳 1朱光发1
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作者信息

  • 1. 100029 首都医科大学附属北京安贞医院呼吸与危重症医学科
  • 折叠

摘要

目的:分析大肠埃希菌所致感染性心内膜炎临床特征、诊断及治疗,以提高对该疾病的认识.方法:报告首都医科大学附属北京安贞医院呼吸与危重症医学科收治的1例大肠埃希菌所致感染性心内膜炎的病例,并以"Escherichia coli、infective Endocarditis"为英文关键词在PubMed进行检索,以"大肠埃希菌、感染性心内膜炎"为关键词在万方数据库、维普数据库进行检索.结果:患者女性,71岁,主因"发热伴咳嗽、咳痰、呼吸困难7d"入院.血液培养和尿液培养均提示大肠埃希菌生长.超声心动图提示主动脉瓣三瓣缘增厚,无冠瓣回声粗糙、增强,瓣体似可见回声中断,舒张期瓣体脱向左心室流出道,考虑主动脉瓣赘生物形成并穿孔,主动脉瓣脱垂并关闭不全(重度).根据改良Duke标准诊断感染性心内膜炎,给与比阿培南联合莫西沙星静脉抗感染治疗,2周后病情稳定转至当地医院继续治疗.共检索出含病例资料的文献22篇,其中中文0篇,英文22篇,涉及病例数25例.结论:大肠埃希菌引起的感染性心内膜炎发病率低,但病死率高,加深对该疾病的认识,提高诊治水平,降低死亡率.

Abstract

Objective:To analyze the clinical characteristics,diagnosis and treatment of Escherichia coli(E.coli)induced infective endocarditis(IE).Methods:A case of E.coli infective endocarditis admitted to Beijing Anzhen Hospital,Capital Medical University was reported.The key words of"Escherichia coli and infective Endocarditis"were used to search in Wanfang database and VIP database.Results:A 71-year-old female patient was admitted to the hospital due to fever with cough,expectoration,and dyspnea for 7 days.Both blood and urine cultures were suggestive of E.coli growth.Echocardiography showed that ejection fraction was 60%,the edge of the aortic valve was thickened,the echo of the non-coronary valve was rough and enhanced,the echo of the valve body was interrupted,and the valve body was dislodged to the left ventricular outflow tract during diastole,which was considered as aortic valve vegetation formation and perforation,and aortic valve prolapse and insufficiency(severe).Infective endocarditis was diagnosed according to the modified Duke criteria,and biapenem combined with moxifloxacin was given intravenous anti-infective treatment.Two weeks later,the condition was stable and the patient was transferred to a local hospital for further treatment.A total of 22 articles with case data were retrieved,including 22 English articles and 0 Chinese articles,involving 25 cases.Conclusion:The incidence of infective endocarditis caused by Escherichia coli is low,but the mortality is high.To deepen the understanding of the disease,improve the level of diagnosis and treatment,and reduce the mortality.

关键词

大肠埃希菌/感染性心内膜炎/菌血症

Key words

Escherichia coli/Infective endocarditis/Bacteremia

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出版年

2024
心肺血管病杂志
北京市心肺血管疾病研究所,首都医科大学附属北京安贞医院

心肺血管病杂志

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影响因子:1.214
ISSN:1007-5062
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