超声在克罗恩病靶向治疗早期疗效评估中的应用
Early Efficacy Assessment of Targeted Therapy for Crohn's Disease by Ultrasound
秦菁 1朱庆莉2
作者信息
- 1. 中国医学科学院北京协和医学院, 北京 100730;中国医学科学院北京协和医院超声医学科, 北京 100730
- 2. 中国医学科学院北京协和医院超声医学科, 北京 100730
- 折叠
摘要
克罗恩病(Crohn's disease,CD)是一种发病机制复杂的慢性炎症性肠病.近年来,靶向治疗的广泛应用显著改善了CD患者的预后.若能在靶向治疗早期进行疗效评估,将有利于筛选出治疗获益的患者,同时可对治疗无效的患者及时调整治疗方案.超声在CD活动性评估、疗效评价方面具有准确性高、无电离辐射、患者接纳程度高的优势,在CD早期疗效评估方面具有潜在临床应用价值.本文就超声在CD靶向治疗早期疗效评估中的应用进行综述,以期为优化CD患者的治疗方案提供借鉴.
Abstract
Crohn's disease(CD)is a chronic inflammatory bowel disease with complicated patho-genesis and prolonged condition.In recent years,with the development of targeted therapy,biological a-gents have been widely used in the treatment of CD,which has significantly improved the prognosis of CD patients.If the efficacy evaluation can be carried out at the early stage of targeted therapy,it may help to figure out the patients who can benefit from the treatment and optimize the treatment plan for the ineffective patients in time.In the evaluation of CD activity and efficacy,ultrasound has the advantages of high accu-racy,no radiation and high patient acceptance,and therefore has potential clinical application value in the early efficacy evaluation of CD targeted therapy.This article reviews the research progress to provides a ref-erence for optimizing the treatment plan for CD patients.
关键词
超声/早期疗效/克罗恩病/靶向治疗Key words
ultrasonography/early efficacy/Crohn's disease/targeted therapy引用本文复制引用
基金项目
中央高水平医院临床科研专项(2022-PUMCH-C-018)
国家自然科学基金(81791640)
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据