Hospital acquired infections in critically ill patients are characterized by high incidence and poor prognosis,but the specific population may benefit from pharmacologic prophylaxis.For patients with ventilator-associated pneumonia,prophylaxis with systemic application or nebulized inhalation of antibiotics may be considered as a choice,depending on the characteristics of the patients and the time onset of the dis-ease.For invasive aspergillosis(IA)in the department of critical care medicine,new perception is needed for its diagnosis and the need for prophylactic antifungal therapy should be evaluated for the high-risk group of IA.Reactivation of CMV is not uncommon in the department of critical care medicine,and prophylactic anti-viral treatment may reduce the incidence of reactivation,but whether it improves clinical outcomes requires further exploration.When considering pharmacologic prophylaxis,it is necessary to conduct a thorough risk-benefit assessment of the target population,the type of drugs,and the mode of administration.
关键词
重症医学/医院感染/药物预防
Key words
critical care medicine/hospital acquired infections/pharmacological prophylaxis
维普
万方数据