Molecular Mechanism of the"Battle"between Virus Infection and Host Antiviral Immunity-Apoptosis,Necroptosis and Pyroptosis
Cell death is an important component of host antiviral immunity response,viral infection can cause different forms of host cell death,including the lytic and non-lytic cell death mode.These types of cell death not only eliminate virus-infected cells,but also further promote the host's innate and adaptive immune processes through release of inflammatory factors.On the contrary,viruses have developed different circumvention mechanisms to inhibit cell death and promote itself infection.This review summarized the research progress in the regulation mechanism of virus-host infection and anti-infection immunity struggle-apoptosis,necroptosis and pyroptosis,aiming to provide references for further understanding the viral molecules pathogenesis and developing a new antiviral strategy.
国家科技期刊平台
NSTL
万方数据
