Pregnancy-associated glycoproteins(PAGs)belonging to the multigene family encoded by the aspartic protease gene,are a group of specific glycoproteins synthesized and secreted by placental trophoblast giant cells of artiodactyls,which can be detected in the maternal circulation after embryo attachment.It has the potential to serve multiple functions,including embryonic attachment,placental development,pregnancy maintenance,embryo survival,proteolytic activity,and immune regulation,which are most often used as biomarkers for early pregnancy diagnosis and assessment of embryo loss,as well as indicators of evaluation of fetal viability and monitoring placental health.In this paper,the origins and characteristics and biological functions of the PAGs family and its application in livestock production were reviewed,in order to provide reference for further research of PAGs biological functions and its rapid development in animal husbandry.
关键词
妊娠相关糖蛋白/胎盘/起源及特征/生物学功能/畜牧生产
Key words
pregnancy-associated glycoproteins/placenta/origins and characteristics/biological function/livestock production
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