Research Progress of Applied Research on Listeria monocytogenes Phage
Listeria monocytogenes being a common foodborne pathogen.Food contaminated with this bacterial can cause listeriosis,with clinical manifestations of sepsis and meningitis,and mortality be up to 30％.Listeria monocytogenes can survive under extreme condition such as high salinity,high acidity,and low temperature,so posing a significant threat to the human and animal health.At present,the main method of preventing and treating this disease is the use of antibiotics.However,the multiple drug resistance making the prevention and treatment of listeriosis extraordinarily difficult.The development of phage and related biological agents provides feasible solutions to solve the above problem.This article reviews the applications of Listeria phages in food preservation,biological detection,genetic engineering,and the interaction between phages and hosts,aiming to provide a theoretical basis for Listeria phages in food pollution prevention and control.
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