Application of Irradiation Technology in Vaccine Development
Pathogen inactivation is the most critical and basic technology for producing inactivated vaccines.The ideal inactivation method is to completely inactivate the pathogen and maintain the immunogenicity of the antigen without chemical residues.Compared with traditional inactivation methods,the main advantages of irradiation technology in vaccine development are that it can penetrate the pathogen but causes less damage to the pathogen surface antigens,and does not re-quire the removal of any chemical residues after inactivation.Therefore,irradiation technology is more suitable for developing safe and effective vaccines.This article briefly reviews and summari-zes the history and progress of using irradiation technology in vaccine development,and discusses potential strategies for developing vaccines using radiation technology.
国家科技期刊平台
NSTL
万方数据
