Research Advances in the Mechanism of Parasite-host Interaction Mediated by miRNAs
Parasitic diseases are widespread and pose a serious threat to human health and animal husbandry.miRNAs are a class of highly conserved endogenous non-coding single-stranded small molecule RNAs with a length of approximately 19-24 nt.Parasite will express a large number of miRNAs to mediate its infection to the host,and the expression profiles of the host miRNAs will also change.These miRNAs will affect the host's resistance or susceptibility,and miRNAs have become one of the hot areas to study the interaction mechanism between parasites and host.This article reviews the role of miRNAs expressed by different species of parasites in infecting the host and the regulatory effect of host miRNAs on parasites,aiming to provide therapeutic methods of anti-parasitic infection based on miRNAs.
万方数据
维普
