Research Progress of Coronary Heart Disease Model Pigs
Coronary heart disease(CHD)is a common cardiovascular disease that seriously affects human health worldwide.Considering its complex pathogenesis and the difficulty of treatment,the study of CHD has been paid much attention.In recent years,animal models have played a key role in the study of cardiovascular diseases.The cardiovascular system of pigs is similar to that of humans in terms of anatomical structure and pathophysiological mechanism,so the model pig has been widely recognized as an excellent model in the study of atherosclerosis.By referring to the diagnostic indicators and risk factors of human CHD,this manuscript aims to explore the evaluation criteria and construction methods of pigs with CHD model similar to human,so as to provide a good experimental model for pathogenesis and clinical application studies related to CHD.This review will lay the foundation for the development of new diagnosis and treatment methods for CHD.