Research Progress in the Effect of Oxidative Stress on Uterus and Pregnancy in Female Livestock
Oxidative stress is a state of excessive reactive oxygen species produced by changes of intracellular and extracellular environment,which plays an important role in the regulation of uterine function.In recent years,studies have shown that oxidative stress can regulate the func-tion of the uterus by affecting reproductive hormones,immune responses,regulating uterine en-vironment and cell signaling.In addition,excessive oxidative stress can impair maternal and pla-cental function,closely related to reproductive diseases such as endometrial carcinoma,pre-ec-lampsia,gestational diabetes mellitus,and intrauterine growth retardation.This paper reviewed the research progress on the regulation of oxidative stress on the uterine function of female live-stock in recent years,in order to better understanding the effect of oxidative stress on the uterine function of female animals,providing new theoretical guidance and practical application for im-proving the reproduction efficiency of female livestock.