The Changes of Blood Physio-biochemistry,Inflammatory and Hormone Factors in the Angular Limb Deformity Foals and Their Mares
The aim of the study is to investigate the incidence rate of Angular Limb Deformities(ALDs)in newborn foals,to compare the differences of blood physio-biochemistry,the inflam-matory factors and the hormones in ALDs foals and their mares with the normal counterparts.Four hundred and sixty newborn foals at the age of 2-28 days were clinically surveyed,the ALDs foals were diagnosed by clinical observation combined with the X-ray imaging.The blood physio-biochemical indices,the inflammatory factors,and the hormones in ALDs foals and their mares were measured in the comparison with those in their normal counterparts.The results showed that 30 newborn foals were found with limb abnormalities,accounting for 6.52％of all investiga-ted foals,in which 16 foals were diagnosed as ALD suffers,and accounting for 53％of all limb abnormality foals.The incidence rate of ALDs was 3.48％.The monocytes and eosinophils of ALDs foals were significantly higher than those of normal foals,and the average red blood cell volume and average red blood cell hemoglobin content of ALDs mares were significantly higher than those of normal mares.The blood calcium,blood phosphorus,blood glucose,creatinine,and magnesium levels of ALDs foals were significantly lower than those of normal foals,while al-kaline phosphatase,total protein,and albumin were significantly higher than those of normal foals;the blood calcium,Serum phosphorus,blood sugar,total bilirubin,triglycerides,total cholesterol,and magnesium levels were significantly lower than those of normal mares,while as-partate aminotransferase,alkaline phosphatase,and albumin were significantly higher than those of normal mares.The levels of tumor necrosis factor and interleukin 6 in ALDs mares were sig-nificantly higher than those in normal mares,while the levels of interleukin 10 were significantly lower than those in normal mares.The levels of parathyroid hormone and 1,25-dihydroxyvitamin D3 in ALDs foals were significantly higher than those in normal foals.There were no significant changes in the remaining indicators.Our study has ascertained the current incidence of ALDs in newborn foals in Zhaosu Count,Xinjiang.That the significant changes in calcium,phosphorus,blood lipid metabolism,and the specific hormone in ALDs foals and their mares compared with normal controls are closely associated with the newborn foal'bone development abnormalities and the occurrence of ALDs.This study provides blood physiological and biochemical data sup-port for revealing the cause of ALDs,and has important clinical reference value for the early aux-iliary diagnosis of ALDs.
万方数据
维普
