首页|Significant genomic introgression from grey junglefowl(Gallus sonneratii)to domestic chickens(Gallus gallus domesticus)

Significant genomic introgression from grey junglefowl(Gallus sonneratii)to domestic chickens(Gallus gallus domesticus)

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Background Chicken is one of the most numerous and widely distributed species around the world,and many studies support the multiple ancestral origins of domestic chickens.The research regarding the yellow skin pheno-type in domestic chickens(regulated by BCO2)likely originating from the grey junglefowl serves as crucial evidence for demonstrating the multiple origins of chickens.However,beyond the BCO2 gene region,much remains unknown about the introgression from the grey junglefowl into domestic chickens.Therefore,in this study,based on whole-genome data of 149 samples including 4 species of wild junglefowls and 13 local domestic chicken breeds,we explored the introgression events from the grey junglefowl to domestic chickens.Results We successfully detected introgression regions besides BCO2,including two associated with growth trait(IGFBP2 and TKT),one associated with angiogenesis(TIMP3)and two members of the heat shock protein family(HSPB2 and CRYAB).Our findings suggest that the introgression from the grey junglefowl may impact the growth perfor-mance of chickens.Furthermore,we revealed introgression events from grey junglefowl at the BCO2 region in mul-tiple domestic chicken breeds,indicating a phenomenon where the yellow skin phenotype likely underwent strong selection and was retained.Additionally,our haplotype analysis shed light on BCO2 introgression event from different sources of grey junglefowl into domestic chickens,possibly suggesting multiple genetic flows between the grey junglefowl and domestic chickens.Conclusions In summary,our findings provide evidences of the grey junglefowl contributing to the genetic diversity of domestic chickens,laying the foundation for a deeper understanding of the genetic composition within domestic chickens,and offering new perspectives on the impact of introgression on domestic chickens.

BCO2Domestic chickensGrey junglefowlIntrogression

Xiurong Zhao、Junhui Wen、Xinye Zhang、Jinxin Zhang、Tao Zhu、Huie Wang、Weifang Yang、Guomin Cao、Wenjie Xiong、Yong Liu、Changqing Qu、Zhonghua Ning、Lujiang Qu

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National Engineering Laboratory for Animal Breeding,College of Animal Science and Technology,China Agricultural University,Beijing 100193,China

Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin,Xinjiang Production and Construction Corps,Tarim Uni-versity,Alar 843300,China

Beijing Municipal General Station of Animal Science,Beijing 100107,China

Animal husbandry station of Fangcheng-gang,Fangchenggang,Guangxi Province 538001,China

Animal Disease Prevention and Control Center of Fangchenggang,Fangchenggang,Guangxi Province 538001,China

Beijing Agricultural Effect Poultry Industry Co.,Ltd.,Beijing 101100,China

Engineering Technology Research Center of Anti-aging Chinese Herbal Medicine of Anhui Province,Fuyang Normal University,Fuy-ang,Anhui 236037,China

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earmarked fund for the Beijing Agriculture Innovation Consortiumopen project of Xinjiang Production & Construction Corps Key Laboratory of Protection and Utilization of Biological Resources inFuyang Normal University Provincial and Ministerial Open Platform Fund

BAIC06-2023-G01BRZD2104FSKFKT026D

2024

10.1186/s40104-024-01006-7

畜牧与生物技术杂志(英文版)
中国科学技术协会

畜牧与生物技术杂志(英文版)

CSTPCD
影响因子：0.765
ISSN：1674-9782
年,卷(期)：2024.15(4)