首页|1990年至2019年我国心血管疾病负担变化及趋势分析

1990年至2019年我国心血管疾病负担变化及趋势分析

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目的 分析我国 1990 年至 2019 年心血管疾病负担变化及其趋势,为推进我国心血管疾病早防早治及患者健康管理策略提供参考.方法 本研究采用美国华盛顿大学卫生计量与评估研究所 2019 年全球疾病负担研究(GBD 2019)对中国心血管疾病负担的估计,并且采用Joinpoint回归模型分析平均年度变化百分比(AAPC)等指标,对 1990 年至 2019 年全球及我国心血管疾病粗死亡率、标化死亡率和伤残调整生命年(DALYs)进行比较及趋势分析.结果 我国心血管疾病的居民死亡人数、粗死亡率和DALYs自 1990 年的 2 423 990 人、204.78/105和 5 091.03/105,增加至 2019 年的 4 584 273 人、322.30/105 和 6 463.47/105.标化死亡率和标化DALYs自 1990 年的 381.21/105 和 7 412.81/105 降低至 2019 年的 276.94/105 和 4 938.38/105.趋势分析发现,我国心血管疾病粗死亡率 1990 年至 2019 年年均增长 1.81%(95%CI=1.68%~1.94%,P<0.01),标化死亡率年均降低0.89%(95%CI=-1.02%~-0.77%,P<0.01),DALYs年均增长1.01%(95%CI=0.90%~1.11%,P<0.01),标化DALYs年均降低1.26%(95%CI=-1.35%~-1.17%,P<0.01).男女性粗死亡率、标化死亡率和DALYs趋势与总体相同,70岁以下人群DALYs逐年上升[AAPC(95%CI)=0.58%(0.46%~0.71%),P<0.01],70 岁以上人群DALYs逐年下降[AAPC(95%CI)=-0.50%(-0.62%~-0.38%),P<0.01].1990 年至 2019 年期间,我国心血管疾病DALYs标化率远高于高社会人口学指数(SDI)国家,2000 年后高于全球水平,2011 年起高于中高SDI国家水平.结论 基于我国心血管疾病负担的现状及其趋势,对不同人群开展精准健康管理,有助于实现健康老龄化及"健康中国2030"目标.
Changes and trends in the burden of cardiovascular diseases in China from 1990 to 2019
Objective To analyze the changes and trends in the burden of cardiovascular diseases(CVD)in China from 1990 to 2019,providing reference to promoting early prevention,treatment,and health management strategies for patients with CVD in China.Methods The study utilized estimates of the burden of CAD in China from Global Burden of Disease Study 2019(GBD 2019)by the Institute for Health Metrics and Evaluation,University of Washington to compare and analyze the trends of crude mortality,standardized mortality,and disability-adjusted life years(DALYs)for CVD in China and globally from 1990 to 2019,and Joinpoint regression model was applied to analyze the average annual percentage change(AAPC)and other indicators.Results From 1990 to 2019,the number of deaths,crude mortality and DALYs for CVD in China increased from 2 423 990,204.78/105 and 5 091.03/105 to 4 584 273,322.30/105 and 6 463.47/105,respectively.The standardized mortality and standardized DALYs decreased from 381.21/105 and 7 412.81/105 in 1990 to 276.94/105 and 4 938.38/105 in 2019.From 1990 to 2019,trend analysis revealed an annual average increase of 1.81%in the crude mortality(95%CI=1.68%-1.94%,P<0.01),a yearly decrease of 0.89%in the standardized mortality(95%CI=-1.02%--0.77%,P<0.01),an annual increase of 1.01%in DALYs(95%CI=0.90%-1.11%,P<0.01),and a yearly decrease of 1.26%in the standardized DALYs(95%CI=-1.35%--1.17%,P<0.01).The trends in crude mortality,standardized mortality,and DALYs for both males and females were consistent with the overall trend.DALYs in people under 70 years old increased annually[AAPC(95%CI)=0.58%(0.46%-0.71%),P<0.01],while DALYs in people over 70 years old showed a yearly decline[AAPC(95%CI)=-0.50%(-0.62%--0.38%),P<0.01].From 1990 to 2019,China's standardized DALYs rate for CVD was much higher than that in countries with high sociodemographic index(SDI),surpassing global levels after 2000 and exceeding the levels of countries with medium-high SDI since 2011.Conclusion Based on the current situation and trends in the burden of CVD in China,implementing precise health management for different populations will help to achieve the goals of healthy aging and healthy China 2030.

Cardiovascular diseasesDisease burdenDisability-adjusted life yearsMortalityTrend analysis

张兆毓、杨时佳、李小攀、刘明

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200032 上海,复旦大学附属中山医院健康管理中心

心血管疾病 疾病负担 伤残调整生命年 死亡率 趋势分析

2024

心脑血管病防治
浙江省心脑血管病防治办公室,浙江省预防医学会,浙江医院

心脑血管病防治

CSTPCD
影响因子:0.638
ISSN:1009-816X
年,卷(期):2024.24(2)
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