Clinical efficacy of enhanced external counterpulsation in the treatment of chronic heart failure:a Meta-analysis
Objective To evaluate the clinical efficacy of enhanced external counterpulsation(EECP)in the treatment of patients with chronic heart failure by meta-analysis.Methods Chinese(CNKI,Wanfang,VIP,SinoMed)and English(Cochrane Library,Embase,Web of Science,PubMed)databases were retrieved to collect randomized controlled trials(RCTs)of EECP in the treatment of chronic heart failure.After screening the literatures and extracting the data,meta-analysis was performed using Revman 5.4 software.Sensitivity analysis and subgroup analysis were used to assess the data and funnel plot was used to evaluate publication bias.Results A total of 14 RCTs involving 1 300 patients were included.Based on the clinical efficacy of different courses of EECP for chronic heart failure,the results showed that compared to the control group,patients in the observation group had longer 6-minute walk distance(6MWD)[MD(95%CI)=56.24(44.48-68.00),P<0.01],lower N-terminal pro-B-type natriuretic peptide(NT-proBNP)level[MD(95%CI)=-371.29(-642.63--99.95),P<0.01]and higher left ventricular ejection fraction(LVEF)level[MD(95%CI)=3.75(2.50-5.01),P<0.01]after treatment.There was no statistically significant difference in adverse reactions between the two groups[OR(95%CI)=1.62(0.69-3.76),P>0.05].Conclusion EECP therapy has good clinical efficacy,and is safe and reliable for patients with chronic heart failure.
国家科技期刊平台
NSTL
万方数据
维普
