首页|基于影像的冠状动脉生理学功能评估研究进展

基于影像的冠状动脉生理学功能评估研究进展

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  • 国家科技期刊平台
  • NETL
  • NSTL
  • 万方数据
  • 维普
血流储备分数(FFR)已经成为评估冠状动脉狭窄程度、指导血运重建策略以及选择治疗方案的冠状动脉生理学"金标准".然而,由于FFR评估过程中存在压力导丝侵入性操作、充血药物的使用等诸多因素,其在临床实践中的应用受到限制.随着冠状动脉虚拟生理学的应用,基于冠状动脉影像衍生FFR的技术得以研发,如冠状动脉造影衍生FFR、光学相干断层成像(OCT)衍生的FFR以及血管内超声(IVUS)衍生的FFR.同时这些功能学评估手段的诊断效能不断被大量临床研究证实.本文旨在对基于冠状动脉造影、IVUS和OCT衍生的FFR的诊断效能、临床运用等方面进行综述.
Research progress in the imaging-based functional assessment of coronary artery physiology
Fractional flow reserve(FFR)has become the reference standard of coronary artery physiology for assessing the degree of coronary stenosis,guiding the revascularization strategy and chosing treatment plans.However,the application of FFR in clinical is limited due to many factors including the invasive procedure of pressure guide wire during FFR evaluation,the use of hyperemic agents and so on.With the application of coronary artery virtual physiology,the coronary imaging derived FFR technology has been developed,such as coronary angiography derived FFR,optical coherence tomography derived FFR and intravascular ultrasound derived FFR.At the same time,the diagnostic efficacy of these functional assessment methods has been confirmed by a large number of clinical studies.This paper aims to review the diagnostic efficacy and clinical use of FFR based on coronary angiography,intravascular ultrasound and optical coherence tomography.

Coronary artery diseaseFractional flow reserveCoronary angiographyOptical coherence tomographyIntravascular ultrasoundPhysiological functional assessment

黄文豪、张靖媛、刘亚君、杜常青

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310000 杭州,浙江中医药大学第二临床医学院

310013 杭州,浙江医院心血管内科

冠状动脉疾病 血流储备分数 冠状动脉造影 光学相干断层成像 血管内超声 生理功能学评估

浙江省自然科学基金

LY21H020002

2024

10.3969/j.issn.1009-816x.2024.02.008

心脑血管病防治
浙江省心脑血管病防治办公室,浙江省预防医学会,浙江医院

心脑血管病防治

CSTPCD
影响因子：0.638
ISSN：1009-816X
年,卷(期)：2024.24(2)
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