基于影像的冠状动脉生理学功能评估研究进展
Research progress in the imaging-based functional assessment of coronary artery physiology
黄文豪 1张靖媛 1刘亚君 1杜常青2
作者信息
- 1. 310000 杭州,浙江中医药大学第二临床医学院
- 2. 310013 杭州,浙江医院心血管内科
- 折叠
摘要
血流储备分数(FFR)已经成为评估冠状动脉狭窄程度、指导血运重建策略以及选择治疗方案的冠状动脉生理学"金标准".然而,由于FFR评估过程中存在压力导丝侵入性操作、充血药物的使用等诸多因素,其在临床实践中的应用受到限制.随着冠状动脉虚拟生理学的应用,基于冠状动脉影像衍生FFR的技术得以研发,如冠状动脉造影衍生FFR、光学相干断层成像(OCT)衍生的FFR以及血管内超声(IVUS)衍生的FFR.同时这些功能学评估手段的诊断效能不断被大量临床研究证实.本文旨在对基于冠状动脉造影、IVUS和OCT衍生的FFR的诊断效能、临床运用等方面进行综述.
Abstract
Fractional flow reserve(FFR)has become the reference standard of coronary artery physiology for assessing the degree of coronary stenosis,guiding the revascularization strategy and chosing treatment plans.However,the application of FFR in clinical is limited due to many factors including the invasive procedure of pressure guide wire during FFR evaluation,the use of hyperemic agents and so on.With the application of coronary artery virtual physiology,the coronary imaging derived FFR technology has been developed,such as coronary angiography derived FFR,optical coherence tomography derived FFR and intravascular ultrasound derived FFR.At the same time,the diagnostic efficacy of these functional assessment methods has been confirmed by a large number of clinical studies.This paper aims to review the diagnostic efficacy and clinical use of FFR based on coronary angiography,intravascular ultrasound and optical coherence tomography.
关键词
冠状动脉疾病/血流储备分数/冠状动脉造影/光学相干断层成像/血管内超声/生理功能学评估Key words
Coronary artery disease/Fractional flow reserve/Coronary angiography/Optical coherence tomography/Intravascular ultrasound/Physiological functional assessment引用本文复制引用
基金项目
浙江省自然科学基金(LY21H020002)
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据