后循环脑梗死轻症患者早期神经功能恶化的危险因素分析
Risk factors for early neurological deterioration of patients with mild posterior circulation cerebral infarction
钱倩 1张静 1边伟林 2邢晓明 1张欣 1白艳梅 1赵小妹 1高娟1
作者信息
- 1. 071000 河北省保定市第一中心医院神经内科
- 2. 071000 河北省保定市人民医院放射科
- 折叠
摘要
目的 探讨美国国立卫生研究院卒中量表(NIHSS)评分≤5分的轻症急性后循环脑梗死(APCCI)患者早期神经功能恶化(END)的危险因素.方法 回顾性收集2019年1月至2021年6月期间,保定市第一中心医院收治的入院时NIHSS评分≤5分的APCCI患者116例,根据是否发生END分为END组与非END组.比较两组的一般资料及临床特征,使用Logistic回归模型分析END的影响因素.结果 21例发生END,发生率为18.10%.以END为终点事件的多变量Logistic回归分析显示,总胆固醇(TC)水平(OR=1.096,95%CI=1.034～1.158)、基线NIHSS评分(OR=2.263,95%CI=1.085～3.441)、大动脉粥样硬化型(OR=1.187,95%CI=1.043～1.332)、中段梗死(OR=4.012,95%CI=1.579～7.688)和肺部感染(OR=1.285,95%CI=1.164～1.406)是APCCI患者发生END的危险因素(P<0.05).结论 高水平TC、基线NIHSS评分高、大动脉粥样硬化型、中段梗死和合并肺部感染是轻症APCCI患者发生END的危险因素.
Abstract
Objective To investigate the risk factors for early neurological deterioration(END)in patients with mild acute posterior circulation cerebral infarction(APCCI)assessed by National Institute of Health Stroke Scale(NIHSS)score≤5.Methods Data of 116 APCCI patients admitted to Baoding NO.1 Central Hospital from January 2019 to June 2021 were collected,all with NIHSS score≤5 on admission.Patients were divided into END group and non-END group based on END occurrence.General data and clinical characteristics of the two groups were compared,and influencing factors for END were analyzed using Logistic regression model.Results Twenty-one patients experienced END,with an incidence of 18.10%.Multivariate Logistic regression analysis with END as the outcome event showed that total cholesterol(TC)level(OR=1.096,95%CI=1.034-1.158),baseline NIHSS score(OR=2.263,95%CI=1.085-3.441),large-artery atherosclerosis(OR=1.187,95%CI=1.043-1.332),middle segment cerebral infarction(OR=4.012,95%CI=1.579-7.688)and pulmonary infection(OR=1.285,95%CI=1.164-1.406)were risk factors for END in APCCI patients(P<0.05).Conclusion High TC level,high baseline NIHSS score,large-artery atherosclerosis,middle segment cerebral infarction and pulmonary infection are risk factors for END in patients with mild APCCI.
关键词
后循环脑梗死/早期神经功能恶化/危险因素Key words
Posterior circulation cerebral infarction/Early neurological deterioration/Risk factors引用本文复制引用
基金项目
河北省卫生健康委科研项目(20220288)
出版年
2024
国家科技期刊平台
NSTL
万方数据