首页|冠状动脉易损斑块的临床研究进展

冠状动脉易损斑块的临床研究进展

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冠状动脉易损斑块容易破裂,导致冠状动脉血栓性阻塞,是引发主要心血管不良事件的重要致病机制.斑块破裂和斑块侵蚀是易损斑块的两种主要表型,具有不同的临床特点和治疗策略.斑块侵蚀患者所引起的心肌梗死范围较小,预后较好.多模式血管内影像学技术的整合应用有助于评估斑块不稳定性,提高诊断准确度和治疗效果.本文就近年来冠状动脉易损斑块的临床研究进展进行综述.
Recent advances in clinical research on coronary vulnerable plaque
Vulnerable plaques in the coronary arteries are prone to rupture,leading to thrombotic obstruction of the coronary artery,which is a significant pathogenic mechanism of major adverse cardiovascular events.Vulnerable plaques can manifest as two main phenotypes:plaque rupture and plaque erosion,each having distinct clinical characteristics and treatment strategies.Patients with plaque erosion tend to have smaller myocardial infarct size and better prognosis.The integration of multi-modality intravascular imaging techniques helps in assessing plaque instability,thereby improving diagnostic accuracy and treatment efficacy.This article provides a comprehensive review of the clinical research advancements in vulnerable plaques in recent years.

Vulnerable plaqueMajor adverse cardiovascular eventsIntravascular imaging techniques

王逸轩、代杨、丁风华、沈迎

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200025 上海,上海交通大学医学院附属瑞金医院心脏科

易损斑块 主要心血管不良事件 血管内影像学技术

国家自然科学基金

82170417

2024

心脑血管病防治
浙江省心脑血管病防治办公室,浙江省预防医学会,浙江医院

心脑血管病防治

CSTPCD
影响因子:0.638
ISSN:1009-816X
年,卷(期):2024.24(6)
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