Research progress of fractional flow in the functional assessment of intracranial atherosclerotic stenosis
Intracranial atherosclerotic stenosis(ICAS)is one of the main causes of ischemic stroke.Currently,the indications for ICAS interventional therapy mostly depend on the degree of stenosis shown by cerebral angiography,but this is limited to morphological assessment and does not consider the functional factors of the narrowed blood vessels,which is widely recognized as a limitation in practical applications.Fractional flow reserve(FFR)is an important tool for functional assessment of coronary artery stenosis and is currently considered as the gold standard for intervention therapy for coronary artery stenosis.Inspired by the concept of"pan-vascular disease",some scholars have introduced the concept of FFR into the field of ICAS,calling it fractional flow or translesional pressure ratio,and have conducted a series of studies in hopes of providing more precise guidance for the diagnosis and treatment of ICAS based on preoperative assessment of fractional flow.This article provides a review of the research progress on fractional flow in the functional assessment of ICAS.
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