Research progress of subclinical cardiotoxicity associated with clozapine
Clozapine(CZP)is effective in treating schizophrenia,especially treatment-resistant schizophrenia.However,some patients with schizophrenia treated with CZP can produce cardiotoxicity,which including myocarditis,cardiomyopathy,subclinical cardiotoxicity,etc.Less attention has been paid to CZP-induced subclinical cardiotoxicity,and the mechanism remains unclear.This paper summarizes the subclinical cardiotoxicity associated with CZP and its possible mechanisms.