Explorations of multidisciplinary therapy mode in prenatal diagnostic practice of fetal neurosurgery
Objective To explore the effectiveness of multidisciplinary diagnosis of fetal neurological diseases.Methods From January 2015 to December 2019,a retrospective study was conducted for fetuses with abnormal nervous system.The relevant clinical data were recorded,including maternal pregnancy,ultrasonic findings,magnetic resonance imaging(MRI),chromosome group diagnosis,invasive examinations,prenatal diagnosis,treatments,deliverymode,postpartum diagnosis and outcomes.Results Among 1065 fetal anomalies diagnosed antenatally,27.3％(291/1065)were primarily neurological in origin.Complete follow-ups accounted for 74.91％(218/291),all completed ultrasonic examinations and MRI accounted for 84.8％(185/218).Maternal age was(27.3±5.4)(20-43)year and gestational age(26.6±1.4)(22.1-34.8)weeks.Among them,ventriculomegaly accounted for 72.93％(159/218),encephalless &deuded 5.50％(12/218),encephalocele 4.13％(9/218),myelomeningocele 10.09％(22/218),corpus callosum dysplasia 4.13％(9/218),posterior fossa cystic malformation 7.34％(16/218)and microcephaly 0.92％(2/218).The postpartum clinical diagnostic coincidence rate was 42.66％(93/218).Termination of pregnancy accounted for 16.97％(37/218),labor induction 1.38％(3/218)and stillbirth 5.50％(12/218).Conclusion The standardized prenatal diagnostic model of MDT provides an accurate prognosis.It is of great significance for reducing severe neurological birth defects.
Nervous system diseasesPrenatal screeningMultidisciplinary therapy
万方数据
维普
