Surgical interventions and prognostic outcomes of congenital esophageal atresia for a decade at a single center
Objective To summarize the clinical features of esophageal atresia(EA)over the last decade at a single center and to explore its related prognostic factors.Methods From June 2009 to December 2018,the relevant clinical data were retrospectively reviewed for 259 EA children.Postoperative follow-up profiles were collected,including complications,medium/long-term clinical symptoms and growth & development status.Results Among them,213 cases were operated and 19 cases refused surgery.And 194(194/213,91.1％)were discharged after recovery.Clinical types were A(n=11),C(n=179),D(n=1)and E(n=3).Open surgery(n=99)and thoracoscopy(n=80)were performed.The incidence of esophageal stenosis(ES)was significantly lower in open surgery group than that in thoracoscopic group(55.0％vs 39.4％,P＜0.05).However,thoracoscopy was not an independent influencing factor of ES.No risk factors of anastomotic leakage were detected.Anastomotic leakage was an independent risk factor of recurrent tracheoesophageal fistula.Prolonged eating(65％,81/125)was one major postoperative clinical symptom.Reflux or heartburn was also common(33.6％,42/125)and＞1.6％of them required surgical intervention.Scoliosis(5.6％,7/125)was generally idiopathic.One complicated case of spinal developmental malformation underwent surgery.Overall growth and development were decent.Only 8.8％of them developed growth retardation.A history of complex esophageal surgery was an influencing factor for growth retardation.Conclusion The overall prognosis of EA is generally favorable.However,long-term follow-ups are required.
Esophageal atresiaPrognosisComplicationGrowth and development
万方数据
维普
