Research advances in musculoskeletal infection in children with negative bacterial culture
Staphylococcus aureus is the most common pathogen cultured for musculoskeletal infection in children.However,in clinical practices,culture is often negative and no pathogen is detected.For culture-negative musculoskeletal infections,there is no indication for antibiotics because of an absence of pathogenic bacteria and drug sensitivity.This review focused upon the problems related to culture-negative musculoskeletal infection to provide references for clinicians in a proper management.