Research advances in the origin of neuroblastoma cells
As the most common extracranial solid tumor in children,neuroblastoma(NB)has complex and diversity biological behaviors.It is well-known that NB is derived from different cells of adrenal gland and along sympathetic ganglia chain.Neural crest cells(NCCs),adrenal chromaffin cells,sympathoblasts and Schwann cell precursors(SCPs)may be the developmental origins of NB cancer cells.This review focused upon the origin of cells to provide references for clinical study of NB.
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