The effect of rituximab on platelet transfusion in ITP patients:a clinical observation
Objective Platelet transfusion refractoriness(PTR)is common in patients with primary immune thrombocytopenia(ITP).This study retrospectively analyzed the changes of platelet transfusion efficiency in ITP patients before and after treatment with rituximab.Methods The clinical materials of 6 ITP patients who had a history of platelet transfusion before and after using rituximab were retrospectively collected,and the patients'platelet counts before and after treatment and the changes in the corrected count increment(CCI)after platelet transfusion were observed.Results Among the 6 patients,5 patients had PTR before using rituximab,and 4 patients had no significant improvement in CCI after using rituximab.Conclusion Rituximab is a means of treating ITP patients with immune-based PTR,but its efficacy needs further verification.
万方数据
维普
