Incidence of venous thrombosis and analysis of the related risk factors in hospitalized patients
Objective To investigate the incidence of venous thromboembolism(VTE),pulmonary embolism(PE)and the proportion of anticoagulant treatment,and their trends in hospitalized patients.Method The Big Data Retrieval System of Hunan Provincial People's Hospital was used to review the incidence of venous thromboembolism(VTE)and pulmonaryo embolism(PE),as well as the number of anticoagulant users in hospitalized patients of different gender,age,and underlying diseases from January 2016 to December 2022,and to compare the effects of various factors on the incidence and the risk ratio(RR)of VTE and PE.Results From 2016 to 2022,the total number of discharged patients was 941 695,including 495 653 males and 437 052 females.The overall incidence of VTE and PE were 1.18%and 0.20%,respectively;they increased from 0.23%and 0.03%in 2016 to 2.51%and 0.30%in 2022(P<0.001).The incidence of VTE and PE in male patients were 1.25%and 0.24%,respectively,which was higher than 1.1%and 0.17%in female patients(P<0.001).The mortality among patients with VTE and PE was higher than that of the overall inpatients(P<0.001).The anticoagulant rate was positively correlated with the incidence of VTE and PE in patients with different diseases.The mortality of patients with VTE and PE was higher than that of all hospitalized patients(P<0.001).The diseases with the highest incidence of VTE were spinal cord injury(17.57%),severe infections(sepsis 13.96%,severe pneumonia 12.76%,bloodstream infection 13.31%),acute respiratory distress syndrome(12.8%),femoral and hip fractures(10.91%and 10.33%respectively),shock(9.91%),and intracranial hemorrhage(8.90%)(when compared with the overall VTE incidence,all P<0.001).The overall anticoagulant rate increased year by year and was positively correlated with the incidence of VTE and PE in patients with underlying diseases(P<0.001).Conclusions The rate of prophylactic anticoagulation in hospitalized patients has increased year by year,but the incidence of VTE and PE is still increasing.Some diseases such as spinal cord injury,severe infections,ARDS,lower limb fractures,shock,and intracranial hemorrhage,etc.were associated with persistently high incidences of VTE and PE.Greater emphasis should be placed on prophylaxis and control in these patients.
NETL
NSTL
万方数据
