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化学发光免疫测定甲状腺功能在生化检验中的准确度分析

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目的 系统分析化学发光免疫测定甲状腺功能在生化检验中的准确度.方法 选取2021年2月—2022年2月湖北省公安县人民医院收治的45例疑似甲状腺疾病患者作为研究对象,以最终的病理诊断结果作为金标准,分别对45例疑似甲状腺疾病患者开展放射免疫分析法与化学发光免疫法进行检测,对比两种检查方法准确度、敏感度、特异度.结果 化学发光免疫法的敏感度、准确度分别为97.50%、95.56%,高于放射免疫分析法的75.00%、73.33%,差异有统计学意义(χ2=8.538、8.459,P均<0.05);化学发光免疫法的特异度为80%,高于放射免疫分析法的60.00%,差异无统计学意义(χ2=0.476,P>0.05).结论 化学发光免疫法检测甲状腺疾病患者的敏感度、特异度、准确度均较高,可为临床医生诊断与治疗甲状腺疾病提供良好的新思路.
Accuracy Analysis of Chemiluminescent Immunoassay of Thyroid Func-tion in Biochemical Test
Objective To systematically analyze the accuracy of chemiluminescent immunoassay of thyroid function in biochemical tests.Methods 45 patients with suspected thyroid disease admitted to Gongan County People's Hospital of Hubei Province from February 2021 to February 2022 were selected as the research objects.With the final patho-logical diagnosis results as the gold standard,45 patients with suspected thyroid disease were detected by radioimmu-noassay and chemiluminescence immunoassay,respectively.The accuracy,sensitivity and specificity of the two meth-ods were compared.Results The sensitivity and accuracy of chemiluminescence immunoassay were 97.50%and 95.56%,respectively,higher than those of radioimmunoassay(75.00%,73.33%),and the differences weres tatistically significant(χ2=8.538,8.459,both P<0.05).The specificity of chemiluminescence immunoassay was 80%,higher than that of radioimmunoassay(60.00%),and the difference was not statistically significant(χ2=0.476,P>0.05).Conclu-sion The sensitivity,specificity and accuracy of chemiluminescence immunoassay in the detection of thyroid diseases are high,which can provide a good new way for clinicians to diagnose and treat thyroid diseases.

Chemiluminescence immunoassayThyroid functionBiochemical testAccuracy

张黎、吴延东、张腾芳

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湖北省公安县人民医院检验科,湖北荆州 434300

化学发光免疫 甲状腺功能 生化检验 准确度

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(1)
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