系统医学2024,Vol.9Issue(1) :53-56.DOI:10.19368/j.cnki.2096-1782.2024.01.053

尿糖与尿微量白蛋白联合检验诊断糖尿病早期肾损伤的价值分析

Analysis of the Value of Urine Glucose and Urinary Microalbumin Com-bined Test in the Diagnosis of Early Renal Injury in Diabetes Mellitus

吴霜 李东风
系统医学2024,Vol.9Issue(1) :53-56.DOI:10.19368/j.cnki.2096-1782.2024.01.053

尿糖与尿微量白蛋白联合检验诊断糖尿病早期肾损伤的价值分析

Analysis of the Value of Urine Glucose and Urinary Microalbumin Com-bined Test in the Diagnosis of Early Renal Injury in Diabetes Mellitus

吴霜 1李东风1
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作者信息

  • 1. 巨野县人民医院检验科,山东菏泽 274900
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摘要

目的 探讨尿糖与尿微量白蛋白联合检验诊断糖尿病早期肾损伤的价值.方法 选取2021年2月—2023年2月巨野县人民医院收治的50例糖尿病早期肾损伤患者为研究组,同时选取50例健康体检者为对照组,均实施尿糖与尿微量白蛋白联合检验,比较尿糖与尿微量白蛋白水平以及诊断效果.结果 尿糖与尿微量白蛋白水平方面,研究组[(3.80±0.74)mmol/L、(27.13±5.71)mg/L]均高于对照组[(2.23±0.53)mmol/L、(16.85±3.50)mg/L],差异有统计学意义(t=12.197、10.854,P均<0.05).尿糖+尿微量白蛋白联合检测的阳性例数为50例,其中真阳性为46例.诊断灵敏度为92.00%、特异度为92.00%、准确度为92.00%、阳性预测值为92.00%,阴性预测值为92.00%,kappa值为0.84.结论 尿糖与尿微量白蛋白联合检验可以获得较高的敏感度、特异度,可为临床诊断糖尿病早期肾损伤提供参考.

Abstract

Objective To explore the value of urine glucose and urine microalbumin combined test in the diagnosis of early diabetic kidney injury.Methods 50 patients with early diabetic kidney injury admitted to Juye County People's Hospital from February 2021 to February 2023 were selected as the study group,and 50 healthy subjects were se-lected as the control group.The combined test of urinary glucose and urinary microalbumin was performed in all pa-tients.The levels of urinary sugar and urinary microalbumin and the diagnostic effect were observed and compared.Results The levels of urinary glucose and urinary microalbumin in the study group[(3.80±0.74)mmol/L,(27.13±5.71)mg/L]were higher than those in the control group[(2.23±0.53)mmol/L,(16.85±3.50)mg/L],and the differences were statistically significant(t=12.197,10.854,both P<0.05).The number of positive cases of urine glucose and urinary mi-croalbumin combined detection was 50,of which 46 were true positive.Diagnostic sensitivity was 92.00%,specificity was 92.00%,accuracy was 92.00%,positive predictive value was 92.00%,negative predictive value was 92.00%,kappa value was 0.84.Conclusion The combined test of urinary glucose and urinary microalbumin can obtain high sensitivity and specificity,which can provide reference for clinical diagnosis of early diabetic kidney injury.

关键词

尿糖/尿微量白蛋白/糖尿病早期肾损伤/灵敏度

Key words

Urine glucose/Urinary microalbumin/Early diabetic kidney injury/Sensitivity

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出版年

2024
系统医学

系统医学

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