首页|不同部位动静脉内瘘对老年糖尿病肾病尿毒症患者血液透析疗效的影响比较

不同部位动静脉内瘘对老年糖尿病肾病尿毒症患者血液透析疗效的影响比较

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目的 比较分析不同部位动静脉内瘘对老年糖尿病肾病尿毒症患者血液透析疗效的影响.方法 选择2019年6月—2023年2月在江苏大学附属人民医院治疗的78例老年糖尿病肾病尿毒症患者,根据动静脉内瘘部位不同将患者均分为3组,即低位内瘘组(n=26)、中位内瘘组(n=26)、高位内瘘组(n=26).低位内瘘组于腕横纹上2~3 cm处内瘘,中位内瘘组于距肘横纹中点下方2~3 cm处内瘘,高位内瘘组于距肘横纹上方约2 cm处内瘘.对3组透析充分性、贫血状态、并发症发生情况进行观察比较.结果 低位内瘘组尿素氮清除率、尿素氮下降率、血管通路血流量均明显低于中位内瘘组,中位内瘘组尿素氮清除率、尿素氮下降率、血管通路血流量均明显低于高位内瘘组,差异有统计学意义(P均<0.05).低位内瘘组血红蛋白、铁蛋白、白蛋白水平均明显低于中位内瘘组,中位内瘘组血红蛋白、铁蛋白、白蛋白水平明显均低于高位内瘘组,差异有统计学意义(P均<0.05).低位内瘘组、中位内瘘组并发症发生率分别为3.85%、7.69%,均明显低于高位内瘘组的30.77%,差异有统计学意义(P均<0.05).结论 在老年糖尿病肾病尿毒症患者血液透析治疗中,高位动静脉内瘘的透析充分性更高,且能够有效改善贫血状态,但并发症发生率较高.
Comparison of the Effect of Different Parts of Arteriovenous Fistula on He-modialysis in Elderly Diabetic Nephropathy Patients with Uremia
Objective To compare and analyze the effect of different parts of arteriovenous fistula on hemodialysis in elderly diabetic nephropathy patients with uremia.Methods 78 elderly diabetic nephropathy uremia patients treated in the Affiliated People's Hospital of Jiangsu University from June 2019 to February 2023 were selected and divided into three groups according to different locations of arteriovenous fistula,namely,low internal fistula group(n=26),middle internal fistula group(n=26)and high internal fistula group(n=26).The low internal fistula group had internal fistula at 2-3 cm above the wrist stripes,the middle internal fistula group had internal fistula at 2-3 cm below the midpoint of the cubital stripes,and the high internal fistula group had internal fistula at about 2 cm above the cubital stripes.The dialysis adequacy,anemia status and complications of the three groups were observed and compared.Results The urea nitrogen clearance rate,urea nitrogen decline rate and blood flow through vascular access in the low internal fistula group were significantly lower than those in the middle internal fistula group,and the urea nitrogen clearance rate,urea nitrogen decline rate and blood flow through vascular access in the middle internal fistula group were significantly lower than those in the high internal fistula group,the differences were statistically significant(all P<0.05).The levels of hemoglobin,ferritin and albumin in the low internal fistula group were significantly lower than those in the middle internal fistula group,and the levels of hemoglobin,ferritin and albumin in the middle internal fis-tula group were significantly lower than those in the high internal fistula group,the differences were statistically sig-nificant(all P<0.05).The decibels of complication incidence in the low internal fistula group and the middle internal fistula group were 3.85%and 7.69%,which were significantly lower than 30.77%in the high internal fistula group,and the differences were statistically significant(both P<0.05).Conclusion In the hemodialysis treatment of elderly diabetic nephropathy patients with uremia,the dialysis adequacy of high arteriovenous fistula is higher,and it can ef-fectively improve the anemia state,but the complication rate is higher.

Diabetic nephropathyUremiaMaintenance hemodialysisDialysis adequacyComplication

郑强、卞文艳、江春玲

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江苏大学附属人民医院肾内科,江苏镇江 212000

糖尿病肾病 尿毒症 维持性血液透析 透析充分性 并发症

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(1)
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