首页|采用四联疗法联合益生菌治疗老年慢性胃炎伴幽门螺杆菌感染的疗效分析

采用四联疗法联合益生菌治疗老年慢性胃炎伴幽门螺杆菌感染的疗效分析

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目的 分析四联疗法联合益生菌治疗慢性胃炎伴幽门螺杆菌感染的效果.方法 选取2022年4月—2023年4月商河县人民医院中收治80例的慢性胃炎伴有幽门螺杆菌感染患者为研究对象,根据随机数表法分为对照组和观察组,两组各40例.对照组用四联疗法,观察组采用四联疗法与益生菌联合治疗,比较两组的临床疗效.结果 观察组的治疗有效率为97.50%,高于对照组的82.50%,差异有统计学意义(χ2=5.000,P=0.025);观察组不良反应发生率为2.50%,低于对照组的25.00%,差异有统计学意义(P<0.05);观察组的幽门螺杆菌(Helicobacter Pylori,Hp)感染根治率高于对照组,差异有统计学意义(P<0.05).结论 益生菌联合四联疗法治疗慢性胃炎伴幽门螺杆菌感染老年患者,可提升治疗的有效性以及安全性,提高Hp根治率.
Analysis of the Efficacy of Quadruple Therapy Combined with Probiotics in the Treatment of Chronic Gastritis with Helicobacter Pylori Infection in Elderly People
Objective To analyze the effect of the combination of quadruple therapy and probiotic therapy with chronic gastritis with helicobacter pylori infection.Methods 80 cases of chronic patients with gastritis with helico-bacter pylori infection admitted to Shanghe County People's Hospital from April 2022 to April 2023 were selected as the research objects,which were divided into control group and observation group according to the random number table method,with 40 cases in each group.The control group used quadruple therapy,and the observation group used quadruple therapy and probiotics,the clinical efficacy of the two group were compared.Results The treatment re-sponse rate of the observation group was 97.50%,which was higher than 82.50%in the control group,and the differ-ence was statistically significant(χ2=5.000,P=0.025).The incidence of adverse reactions in the observation group was 2.50%,which was lower than 25.00%in the control group,and the difference was statistically significant(P<0.05).The radical cure rate of helicobacter pylori(Hp)infection in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Probiotic therapy combined with qua-druple therapy in the treatment of chronic gastritis with Helicobacter pylori infection in elderly patients will enhance the effectiveness of medication therapy as well as safety,improve the Hp cure rate.

Quadruple therapyProbiotic therapyElderlyChronic gastritisHelicobacter pylori infection

侯建芸、张玉兰、冯会敬

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商河县人民医院消化内科,山东济南 251600

四联疗法:益生菌治疗 老年 慢性胃炎 幽门螺杆菌感染

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(1)
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