Objective To analyze the effect of moxifloxacin combined with brancho fiberoscope(BF)drug perfusion treatment in patients with multidrug resistant tuberculosis(MDR-TB).Methods 120 MDR-TB patients admitted to Heze Infectious Disease Hospital from January 2021 to December 2022 were selected and randomly divided into two groups using a random number table method.The control group(60 cases)received conventional chemotherapy regi-men,while the study group(60 cases)received BF drug perfusion combined with moxifloxacin treatment on the basis of conventional chemotherapy.The clinical efficacy,levels of C-reactive protein(CRP)and procalcitonin(PCT),and adverse reactions were compared between the two groups.Results The total effective rate of the study group patients was 91.67%,which was higher than the control group's 73.33%,and the difference was statistically significant(χ2= 6.984,P<0.05).After treatment,compared with the control group,the CRP and PCT levels in the study group were lower,and the differences were statistically significant(both P<0.05).There was no statistically significant difference in the adverse reactions between the two groups of patients(P>0.05).Conclusion The treatment of MDR-TB patients with BF drug perfusion combined with moxifloxacin can enhance the clinical efficacy,inhibit the inflammatory factors of the body,the safety is more ideal,and it has clinical application value.
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